Genome-wide association and whole exome sequencing studies reveal a novel candidate locus for restless legs syndrome.

Ergun, Ufuk; Say, Bahar; Ergun, Sezen; PERÇİN, FERDA; Inan, Levent; Kaygisiz, Sukran; Asal, Pinar; Yurteri, Buket; Struchalin, Maksim; Shtokalo, Dmitry; Ergun, MEHMET

doi:10.1016/j.ejmg.2021.104186

Genome-wide association and whole exome sequencing studies reveal a novel candidate locus for restless legs syndrome.

Ergun U., Say B., Ergun S. G., PERÇİN F. E., Inan L., Kaygisiz S., ...Daha Fazla

European journal of medical genetics, cilt.64, sa.4, ss.104186, 2021 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 64 Sayı: 4
Basım Tarihi: 2021
Doi Numarası: 10.1016/j.ejmg.2021.104186
Dergi Adı: European journal of medical genetics
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, MEDLINE
Sayfa Sayıları: ss.104186
Anahtar Kelimeler: Restless legs syndrome, Microarray, Linkage analysis, Genome wide association, Whole exome sequencing, BINDING PROTEIN, IDENTIFICATION, EPIDEMIOLOGY, DIAGNOSIS, GENETICS
Gazi Üniversitesi Adresli: Evet

Özet

Introduction: The restless legs syndrome (RLS) is a common heritable neurologic disorder which is characterized by an irresistible desire to move and unpleasant sensations in the legs.