Genome-wide association and whole exome sequencing studies reveal a novel candidate locus for restless legs syndrome.

Ergun, Ufuk; Say, Bahar; Ergun, Sezen; PERÇİN, FERDA; Inan, Levent; Kaygisiz, Sukran; Asal, Pinar; Yurteri, Buket; Struchalin, Maksim; Shtokalo, Dmitry; Ergun, MEHMET

doi:10.1016/j.ejmg.2021.104186

Genome-wide association and whole exome sequencing studies reveal a novel candidate locus for restless legs syndrome.

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Ergun U., Say B., Ergun S. G., PERÇİN F. E., Inan L., Kaygisiz S., ...More

European journal of medical genetics, vol.64, no.4, pp.104186, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 64 Issue: 4
Publication Date: 2021
Doi Number: 10.1016/j.ejmg.2021.104186
Journal Name: European journal of medical genetics
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, MEDLINE
Page Numbers: pp.104186
Keywords: Restless legs syndrome, Microarray, Linkage analysis, Genome wide association, Whole exome sequencing, BINDING PROTEIN, IDENTIFICATION, EPIDEMIOLOGY, DIAGNOSIS, GENETICS
Gazi University Affiliated: Yes

Abstract

Introduction: The restless legs syndrome (RLS) is a common heritable neurologic disorder which is characterized by an irresistible desire to move and unpleasant sensations in the legs.