How Does the Persistent Organic Pollutant Perfluorooctane Sulfonate (PFOS) Affect Health of the Common Carp?

Arslan P., GÜL G., GÜNAL A. Ç.

WATER AIR AND SOIL POLLUTION, cilt.234, sa.10, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 234 Sayı: 10
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1007/s11270-023-06651-8
  • Dergi Adı: WATER AIR AND SOIL POLLUTION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, ABI/INFORM, Agricultural & Environmental Science Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), Artic & Antarctic Regions, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Compendex, Environment Index, Geobase, Greenfile, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Gazi Üniversitesi Adresli: Evet

Özet

Perfluorooctane sulfonate (PFOS, C8F17SO3; CAS No. 2795-39-3), an industrial persistent organic pollutant, has been known with significant bioaccumulation and biomagnification potential. The purpose of this study was to demonstrate the effects of PFOS on the aquatic model vertebrate common carp (Cyprinus carpio). Fish were exposed to 1 and 10 mg/L PFOS during 96 h and 21 days. There were two control groups: control (only fish) and solvent control (DMSO and fish). After exposure times, the blood samples and tissues (gill, liver, muscle, brain, and kidney) were taken from the fish. The physiological (hematocrit) and genotoxic (micronucleus) parameters were done with the blood samples. The biochemical parameters (the advanced oxidative protein products, AOPP and glutathione, GSH) were done with the muscle, gill, brain, and liver samples. While the micronucleus and nuclear abnormalities increased, the hematocrit values decreased in the 1 mg/L PFOS-exposed groups during 96 h and 21 days. The AOPP values of the muscle, gill, brain, and liver tissues significantly changed in PFOS-exposed groups at both exposure times (P < 0.05). Unlike AOPP, glutathione levels of gill did not change in both PFOS-exposed groups at 96 h (P > 0.05). Histopathological changes were seen in the gill, liver, and kidney tissues after exposure to PFOS. Therefore, even low concentrations of PFOS have genotoxic, biochemical, and histopathological effects on carp. The results help to understand the early toxicological effects of PFOS in freshwater ecosystems.