Pharmacokinetics and Bioequivalence study of ranitidine film tablets in healthy male subjects


Gschwend M. H., Guserle R., Erenmemisoglu A., Martin W., Tamur U., Kanzik I., ...More

ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, vol.57, no.6, pp.315-319, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.1055/s-0031-1296625
  • Journal Name: ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.315-319
  • Keywords: CAS 66357-35-5, CAS 66357-59-3, histamine H-2-receptor antagonists, Ranitab (R), ranitidine hydrochloride, bioequivalence, pharmacokinetics, BIOAVAILABILITY, KINETICS
  • Gazi University Affiliated: No

Abstract

The aim of the present study was to compare the bioavailability of ranitidine (CAS 66357-35-5) from two different ranitidine hydrochloride (CAS 66357-59-3) film tablets (Ranitab((R)) 150 mg film tablets as test preparation and 150 mg film tablets of the originator product as reference preparation). The study was conducted according to an open-label, randomised two-period cross-over design with a wash-out phase of 9 days.