Synthesis and Characterization of Iron Oxide Derivatized Mutant Cowpea Mosaic Virus Hybrid Nanoparticles

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Martinez-Morales A. A., Portney N. G., Zhang Y., Destito G., Budak G., ÖZBAY E., ...More

ADVANCED MATERIALS, vol.20, no.24, pp.4816-4821, 2008 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 24
  • Publication Date: 2008
  • Doi Number: 10.1002/adma.200702863
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.4816-4821
  • Gazi University Affiliated: Yes


A novel nanoparticle hybrid is attained by the covalent attachment of iron oxide (gamma-Fe2O3) nanoclusters onto the surface of a mutagenized cow pea mosaic virus (CPMV-T184C). Using a stepwise substrate-based integration, monodisperse CPMV-IO hybrids are anchored on a gold substrate. The physical and magnetic properties of individual CPMV-IO hybrids are qualitatively investigated by atomic/magnetic force microscopy (AFM/MFM). During MFM characterization a 'boundary-effect' is observed at the CPMV/IO interface.