Is tissue-plasminogen activator gene polymorphism a risk factor for venous thromboembolism in every population?


Oguzulgen İ. K. , Ekim N., Erkekol F., Altinok B., Akar N.

Journal of thrombosis and thrombolysis, vol.19, no.1, pp.61-3, 2005 (SCI-Expanded) identifier identifier identifier

Abstract

Background: Tissue-plasminogen activator is a key protein of fibrinolytic system. In recent years the relation between t-PA, its genetic polymorphisms and arterial or venous thrombosis were investigated in different populations. The aim of this study is to investigate the role of t-PA gene polymorphism in Turkish venous thromboembolism (VTE) patients.