Is tissue-plasminogen activator gene polymorphism a risk factor for venous thromboembolism in every population?

Oguzulgen İ. K. , Ekim N., Erkekol F., Altinok B., Akar N.

Journal of thrombosis and thrombolysis, cilt.19, sa.1, ss.61-3, 2005 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 19 Konu: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s11239-005-0941-5
  • Dergi Adı: Journal of thrombosis and thrombolysis
  • Sayfa Sayıları: ss.61-3


Background: Tissue-plasminogen activator is a key protein of fibrinolytic system. In recent years the relation between t-PA, its genetic polymorphisms and arterial or venous thrombosis were investigated in different populations. The aim of this study is to investigate the role of t-PA gene polymorphism in Turkish venous thromboembolism (VTE) patients.