Inhibitory activity of Scorzonera latifolia and its components on enzymes connected with healing process

AKKOL E., Smejkal K., Kurtul E., İlhan M., Guragac F. T., Iscan G. S., ...More

JOURNAL OF ETHNOPHARMACOLOGY, vol.245, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 245
  • Publication Date: 2019
  • Doi Number: 10.1016/j.jep.2019.112168
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Collagenase, Elastase, Flavonoid, Hyaluronidase, Scorzonera latifolia, Wound healing, QUERCETIN, ANTIOXIDANT, FLAVONOIDS, CONSTITUENTS, DEGRADATION, LUTEOLIN, MATRIX, FISCH
  • Gazi University Affiliated: Yes


Ethnopharmacological relevance: Scorzonera latifolia (Fisch. & Mey.) DC. (Asteraceae) grows naturally in Eastern Anatolia, northeastern Iran, and Caucasus. Latex of S. latifolia roots is used in Turkish folk medicine for its analgesic effects, externally to cure infertility in women, and internally as an antihelmintic. The milk obtained from the stem of the Scorzonera species is used for wound healing activity. Antinociceptive, anti-inflammatory, wound-healing, antioxidant, and antimicrobial activities have previously been reported for S. latifolia.