Akademik Veri Yönetim Sistemi
PHYSICAL AND ENGINEERING SCIENCES IN MEDICINE, cilt.46, sa.3, ss.1163-1174, 2023 (SCI-Expanded)
Parkinson's disease (PD) is characterized by slowed movements, speech disorders, an inability to control muscle movements, and tremors in the hands and feet. In the early stages of PD, the changes in these motor signs are very vague, so an objective and accurate diagnosis is difficult. The disease is complex, progressive, and very common. There are more than 10 million people worldwide suffering from PD. In this study, an EEG-based deep learning model was proposed for the automatic detection of PD to support experts. The EEG dataset comprises signals recorded by the University of Iowa from 14 PD patients and 14 healthy controls. First of all, the power spectral density values (PSDs) of the frequencies between 1 and 49 Hz of the EEG signals were calculated separately using periodogram, welch, and multitaper spectral analysis methods. 49 feature vectors were extracted for each of the three different experiments. Then, the performances of support vector machine, random forest, k-nearest neighbor, and bidirectional long-short-term memory (BiLSTM) algorithms were compared using the PSDs feature vectors. After the comparison, the model integrating welch spectral analysis and the BiLSTM algorithm showed the highest performance as a result of the experiments. The deep learning model achieved satisfactory performance with 0.965 specificity, 0.994 sensitivity, 0.964 precision, 0.978 f1-score, 0.958 Matthews correlation coefficient, and 97.92% accuracy. The study is a promising attempt to detect PD from EEG signals and it also provides evidence that deep learning algorithms are more effective than machine learning algorithms for EEG signal analysis.