Exposure to Helicobacter pylori and Serum Kynurenine to Tryptophan Ratio in Patients with Gastric Cancer

ENGİN A. B., KARAHALİL B., Karakaya A. E., Engin A.

PTERIDINES, cilt.21, sa.4, ss.110-120, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1515/pteridines.2010.21.1.110
  • Dergi Adı: PTERIDINES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.110-120
  • Anahtar Kelimeler: Helicobacter pylori, indoleamine 2,3-dioxygenase, tryptophan, kynurenine, neopterin, biopterin, nitric oxide, NITRIC-OXIDE SYNTHASE, INDOLEAMINE 2,3-DIOXYGENASE, INTERFERON-GAMMA, HUMAN-CELLS, DNA-DAMAGE, T-CELL, TETRAHYDROBIOPTERIN, METABOLISM, INHIBITION, EXPRESSION
  • Gazi Üniversitesi Adresli: Evet

Özet

In Helicobacter pylori seropositive individuals, the subsequent risk of non-cardia gastric cancer development is frequently attributed to the infection agent. Although the link between inflammation and gastric cancer is formally recognized, the molecular basis of evading mechanisms of Helicobacter pylori from host immune system remains unclear.