Exposure to Helicobacter pylori and Serum Kynurenine to Tryptophan Ratio in Patients with Gastric Cancer

ENGİN A. B. , KARAHALİL B., Karakaya A. E. , Engin A.

PTERIDINES, vol.21, no.4, pp.110-120, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.1515/pteridines.2010.21.1.110
  • Journal Name: PTERIDINES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.110-120
  • Keywords: Helicobacter pylori, indoleamine 2,3-dioxygenase, tryptophan, kynurenine, neopterin, biopterin, nitric oxide, NITRIC-OXIDE SYNTHASE, INDOLEAMINE 2,3-DIOXYGENASE, INTERFERON-GAMMA, HUMAN-CELLS, DNA-DAMAGE, T-CELL, TETRAHYDROBIOPTERIN, METABOLISM, INHIBITION, EXPRESSION
  • Gazi University Affiliated: Yes


In Helicobacter pylori seropositive individuals, the subsequent risk of non-cardia gastric cancer development is frequently attributed to the infection agent. Although the link between inflammation and gastric cancer is formally recognized, the molecular basis of evading mechanisms of Helicobacter pylori from host immune system remains unclear.