Malignant pleural mesothelioma with scalp, cerebellar, and finger metastases: a rare case.

Kanbay A., Oguzulgen K. I. , Ozturk C., Memis L., Demircan S., Kurkcuoglu C., ...Daha Fazla

Southern medical journal, cilt.100, sa.1, ss.63-5, 2007 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 100 Konu: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1097/smj.0b013e31802e465c
  • Dergi Adı: Southern medical journal
  • Sayfa Sayıları: ss.63-5


Malignant pleural mesothelioma (MPM) is a rare and asbestosis-associated tumor. MPM commonly invades locally, mostly in the lung, heart, pericardium, chest wall, and vertebrae. Distant metastasis of MPM is very rare. Here we report a patient with MPM who presented with multiple unusual distant metastases. The patient's thorax tomography demonstrated right-sided, irregularly-thickened pleura with nodular masses and invasion of the chest wall into the subcutaneous area. The patient underwent biopsy for a subcutaneous mass in the right anterior chest wall. Pathologic examination revealed a malignant mesenchymal tumor. During follow-up, he suffered from a painful nodule on the scalp and nodules on the fingers, as well as weakness in his right ann. Cranial magnetic resonance imaging illustrated a 1 cm nodule in the left cerebellar hemisphere. Histopathologic examination of the biopsy from the nodule on the scalp revealed a typical mixed type of MPM, with calretinin, vimentin and creatine 5/6 positivity. Distant metastases can be seen in MPM and a biopsy of metastatic regions can yield the diagnosis.