Peritumoral Lymphatic Microvessel Density Associated with Tumor Progression and Poor Prognosis in Gastric Carcinoma


Coskun U., AKYÜREK N., DURSUN A., Yamac D.

JOURNAL OF SURGICAL RESEARCH, vol.164, no.1, pp.110-115, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 164 Issue: 1
  • Publication Date: 2010
  • Doi Number: 10.1016/j.jss.2009.03.081
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.110-115
  • Keywords: D2-40, lymphangiogenesis, CD31, gastric carcinoma, prognosis, SQUAMOUS-CELL CARCINOMA, GROWTH-FACTOR-C, NODE METASTASIS, BREAST-CANCER, VESSEL DENSITY, INTRATUMORAL LYMPHATICS, FACTOR-A, LYMPHANGIOGENESIS, ANGIOGENESIS, EXPRESSION
  • Gazi University Affiliated: Yes

Abstract

Background. Lymphangiogenesis and angiogenesis are critical processes for tumor growth, invasion, and metastasis, and are crucial for therapeutic strategies. The aim of the present study was to evaluate the clinical significance of lymphangiogenesis and its regulation in gastric carcinomas.