Akademik Veri Yönetim Sistemi
XXXIII. WASPaLM World Congress & XXIV. National Clinicial Biochemistry Congress , Antalya, Türkiye, 16 - 20 Ekim 2024, ss.125
Aim: Urinary system stones are gaining increasing importance due to their potential to cause extremely severe pain, their role in the development of chronic kidney failure, and their rising incidence in recent times. Determining the composition of the stones is essential for identifying the etiology. This allows for appropriate recommendations (diet etc.) tailored to the stone content and etiology during the treatment process, thereby contributing to the reduction of the high recurrence risk. With the advancement of technology, the analysis of urinary system stones can now be conducted using Fourier Transform Infrared Spectroscopy (FTIR), which is a more reliable method compared to the previously used manual techniques. Methods: Urinary system stone analyses have been performed using the FTIR method at the Gazi University Life Sciences Center under the responsibility of Gazi University Faculty of Medicine Hospital since September 2023. A comprehensive library for stone analysis has been established, and detailed stone analyses have been conducted for 76 patients to date. Results: Among a total of 76 patients, 33 (43.4%) had only one stone, while the others had multiple stones. In 30 patients (39.4%), the stone color was light brown, while the others had stones of various colors. On average, 0.477 grams of stone sample were analyzed from each patient. The stone analysis results showed that the most frequently detected stone types were calcium monohydrate and calcium dihydrate, identified in 59 samples (77.6%). The most common location was the left kidney in 22 patients (28.9%), while the least common location was both kidneys simultaneously in 2 patients (2.6%). Out of the total, 71 patients (93.4%) were referred from the Department of Urology, 2 patients (2.63%) from the Division of Adult Nephrology, 1 patient (1.31%) from the Department of Pediatric Surgery, 1 patient (1.31%) from the Division of Pediatric Hematology, and 1 patient (1.31%) from the Division of Pediatric Nephrology. The gender distribution showed that 52 patients (68.5%) were male and 24 patients (31.5%) were female, with an average age of 44 years. Conclusion: The stone types identified in the analyses are consistent with the literature, with calcium monohydrate and calcium dihydrate stones being the most frequently detected. The detailed stone analyses reported in our laboratory allow for the evaluation of stone type and all other characteristics. This enables the management of the patients' treatment process, reducing risks such as chronic kidney disease and preventing patients from experiencing severe pain by lowering the recurrence risk. It is crucial to analyze stones, which are not extensively analyzed in healthcare institutions in our country, and to preferably use the more reliable and standardized FTIR method over manual techniques.