Sulphasalazine treatment in protracted familial Mediterranean fever arthritis

BAKKALOĞLU EZGÜ S. A., AKSU T., GÖKER B., Unlusoy A., Peru H., Fidan K., ...Daha Fazla

EUROPEAN JOURNAL OF PEDIATRICS, cilt.168, sa.8, ss.1017-1019, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 168 Sayı: 8
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s00431-008-0875-y
  • Dergi Adı: EUROPEAN JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1017-1019
  • Anahtar Kelimeler: Familial Mediterranean fever, Arthritis, Sulphasalazine, INTERFERON-ALPHA, ETANERCEPT, PATIENT
  • Gazi Üniversitesi Adresli: Evet

Özet

Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by self-limited attacks of fever and polyserositis. Articular involvement in early-onset FMF is a common finding characterized by non-erosive, generally asymmetric monoarthritis in large joints. Protracted FMF arthritis was reported in 2.6% of Turkish patients. An 8-year-old female who has a history of FMF for 5 years applied to our hospital with complaints of persistent swelling and pain of her left knee for 8 months. The patient had been tried to be managed with non-steroidal anti-inflammatory drugs as well as intra-articulary steroids and colchicine. However, arthritis and acute phase response persisted. With sulphasalazine, complete recovery was achieved. It is our belief that sulphasalazine can be a choice of medical treatment in protracted FMF arthritis.