Research Information System
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, vol.54, no.2, pp.253-259, 2015 (SCI-Expanded)
A series of sixteen new urea and thiourea derivatives at position 6 of 3-methyl-2(3H)-benzothiazolone ring have been prepared and studied using 1R, H-1 NMR, mass spectra and elemental analysis. The urea and thiourea derivatives have been obtained by the reaction of 6-amino-3-methyl-2(3H)-benzothiazolone with appropriate isocyanates and isothiocyanates. The antibacterial, antifungal and antimycobacterial activities of the synthesized compounds have been evaluated in vitro using microdilution and microplate methods.