Treatment of Severe Refractory Thrombocytopenia in Brucellosis with Eltrombopag: A Case Report

DAŞDEMİR S., UYSAL YAZICI M., GÜDELOĞLU E., AKKUZU E., TEZER H.

PEDIATRIC INFECTIOUS DISEASE JOURNAL, cilt.41, sa.8, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 8
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1097/inf.0000000000003555
  • Dergi Adı: PEDIATRIC INFECTIOUS DISEASE JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: thrombocytopenia, brucellosis, eltrombopag, thrombopoietin receptor agonist, CHILDREN, MANIFESTATION
  • Gazi Üniversitesi Adresli: Evet

Özet

Brucellosis is a zoonotic disease. Severe refractory thrombocytopenia caused by brucellosis is very rare and easily misdiagnosed. We reported a 5-year-old girl who developed severe refractory thrombocytopenia secondary to brucellosis. The first-line treatment including corticosteroids and intravenous immunoglobulin did not elevate her platelets, but eltrombopag worked well and her platelet count recovered rapidly.