Akademik Veri Yönetim Sistemi
Antimicrobial Stewardship & Healthcare Epidemiology, cilt.2, sa.30, ss.1-7, 2022 (Hakemli Dergi)
Objectives:
In this study, we sought to determine the prevalence of
bloodstream infection (BSI) in severe coronavirus disease 2019 (COVID-19)
patients and to determine the risk factors of BSI in critical COVID-19
patients.
Design:
Retrospective, descriptive study between March 2020 and
January 2021.
Setting:
An 1,007-bed university hospital.
Participants:
Patients who were hospitalized due to severe COVID-19
disease and had an aerobic blood culture taken at least once during hospitalization
Methods:
Case definitions were made according to National Institutes
of Health clinical definitions. According to the blood culture results, the
patients were grouped as with and without BSIs, and compared for BSIs risk
factors.
Results:
In total, 195 patients were included in the study. Blood
culture positivity was detected in 76 (39.0%) of 196 patients. Excluding blood
culture positivity considered as contamination, the prevalence of BSI in all
severe COVID-19 cases was 18.5% (n = 36). In intensive care unit patients the
prevalence of BSI was 30.6% (n = 26). In multivariate analyses, central venous
catheter (odds ratio [OR], 8.17; 95% confidence interval [CI], 2.46–27.1; P
< .01) and hospitalization in the multibed intensive care unit (OR, 4.28;
95% CI, 1.28–14.3; P < .01) were risk factors associated with the
acquisition of BSI.
Conclusion:
The prevalence of BSI in COVID-19 patients is particularly
high in critically ill patients. The central venous catheter and multibed
intensive care follow-up are risk factors for BSI. BSIs can be reduced by
increasing compliance to infection control measures and central venous catheter
insertion-care procedures. The use of single-bed intensive care units where
compliance can be achieved more effectively is important for the prevention of
BSIs.