Assessment of Citrullinated Myelin by H-1-MR Spectroscopy in Early-Onset Multiple Sclerosis


Oguz K. K. , Kurne A., Aksu A. O. , KARABULUT E., Serdaroglu A., Teber S., ...More

AMERICAN JOURNAL OF NEURORADIOLOGY, vol.30, no.4, pp.716-721, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 4
  • Publication Date: 2009
  • Doi Number: 10.3174/ajnr.a1425
  • Title of Journal : AMERICAN JOURNAL OF NEURORADIOLOGY
  • Page Numbers: pp.716-721

Abstract

BACKGROUND AND PURPOSE: Myelin instability and citrullinated myelin basic protein have been demonstrated in the brains of patients with chronic and fulminating forms of multiple sclerosis (MS). Our aim was to trace citrulline in the brains of patients with early-onset MS by using proton MR spectroscopy (H-1-MR spectroscopy).