Concentration of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like PCBs in human adipose tissue from Turkish men

Cok İ. , Donmez M. K. , Satiroglu M. H. , Aydinuraz B., Henkelmann B., Kotalik J., ...More

Chemosphere, vol.66, no.10, pp.1955-1961, 2007 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 10
  • Publication Date: 2007
  • Doi Number: 10.1016/j.chemosphere.2006.07.071
  • Title of Journal : Chemosphere
  • Page Numbers: pp.1955-1961


There is no previous report from Turkey on chemically determined polychlorinated dibenzo-para-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (PCBs) in human tissues expressed as World Health Organization (WHO) toxic equivalents (TEQs). The objective of this study was to determine the occurrence of PCDDs/Fs, and dioxin-like PCBs in the general adult Turkish population. For this reason we measured adipose tissue concentrations of PCDDs/Fs and dioxin-like PCBs in 23 Turkish men living in Ankara,Turkey in 2004. PCDD/F concentrations ranged between 3.2 and 19.7 pg WHO-TEQ/g fat (5.34 and 42.7 WHO-TEQ/g fat, respectively, including dioxin-like PCBs). The mean concentrations of WHOPCDD/F-TEQ and WHOPCB-TEQ were 9.2 and 6.67 pg/g on a lipid basis, respectively. Samples were analyzed for PCDD/F and twelve dioxin-like PCB congeners using high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS). This study is very important since it is the first report on PCDDs/Fs and dioxin-like PCB contamination in human adipose tissue from Turkey. © 2006 Elsevier Ltd. All rights reserved.