Oxcarbazepine does not suppress cortical spreading depression

Hoffmann U., Dilekoez E. , Kudo C., Ayata C.

CEPHALALGIA, cilt.31, sa.5, ss.537-542, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Konu: 5
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1177/0333102410388433
  • Dergi Adı: CEPHALALGIA
  • Sayfa Sayıları: ss.537-542


Background: Cortical spreading depression is the electrophysiological substrate of migraine aura, and may trigger headache. Recently, chronic treatment with five migraine prophylactic drugs was shown to suppress cortical spreading depression, implicating spreading depression as a common therapeutic target in migraine prophylaxis.