The effect of calpain-10 gene polymorphism on the development of type 2 diabetes mellitus in a Turkish population

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Arslan E., AÇIK L., Gunaltili G., Ayvaz G., Altinova A., Arslan M.

ENDOKRYNOLOGIA POLSKA, cilt.65, sa.2, ss.90-95, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5603/ep.2014.0013
  • Dergi Adı: ENDOKRYNOLOGIA POLSKA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.90-95
  • Anahtar Kelimeler: Calpain-10, haplotype, SNP, type 2 diabetes, INSULIN-RESISTANCE, ASSOCIATION, VARIANTS, RISK, SECRETION, OBESITY
  • Gazi Üniversitesi Adresli: Evet

Özet

Introduction: The variations in the Calpain-10 gene have been suggested to be related to susceptibility to type 2 diabetes mellitus (T2DM) in different populations. In this study, we investigated the relationship between single nucleotide polymorphism (SNP)-19, -44 and -63 in the Calpain-10 gene and the development of T2DM in a Turkish population.