The role of oxidative DNA damage and GSTM1, GSTT1, and hOGG1 gene polymorphisms in coronary artery disease risk

KADIOĞLU, ELA; TAÇOY, GÜLTEN; Ozcagli, Eren; Okyay, Kaan; Akboga, Mehmet; Cengel, Atiye; Sardas, Semra

doi:10.14744/anatoljcardiol.2016.6697

The role of oxidative DNA damage and GSTM1, GSTT1, and hOGG1 gene polymorphisms in coronary artery disease risk

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KADIOĞLU E. , TAÇOY G. , Ozcagli E., Okyay K., Akboga M. K. , Cengel A., ...More

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.16, no.12, pp.931-938, 2016 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 16 Issue: 12
Publication Date: 2016
Doi Number: 10.14744/anatoljcardiol.2016.6697
Title of Journal : ANATOLIAN JOURNAL OF CARDIOLOGY
Page Numbers: pp.931-938

Abstract

Objective: Atherosclerotic coronary artery disease (CAD) appears to be a multifactorial process caused by the interaction of environmental risk factors with multiple predisposing genes. Therefore, in this study we aimed to determine the role of oxidative DNA damage and some variations in glutathione S-transferase (GSTM1 and GSTT1) and DNA repair (hOGG1) genes in CAD risk.