The role of oxidative DNA damage and GSTM1, GSTT1, and hOGG1 gene polymorphisms in coronary artery disease risk.

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KADIOĞLU E., TAÇOY G., Ozcagli E., Okyay K., Akboga M. K., Cengel A., ...Daha Fazla

Anatolian journal of cardiology, cilt.16, sa.12, ss.931-938, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 12
  • Basım Tarihi: 2016
  • Doi Numarası: 10.14744/anatoljcardiol.2016.6697
  • Dergi Adı: Anatolian journal of cardiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.931-938
  • Anahtar Kelimeler: coronary artery disease, DNA damage, GSTM1, GSTT1, hOGG1, S-TRANSFERASE GENES, LYMPHOCYTE DNA, TURKISH POPULATION, CIGARETTE-SMOKING, HEART-DISEASE, REPAIR GENES, SUSCEPTIBILITY, STRESS, CANCER, ASSOCIATION
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Atherosclerotic coronary artery disease (CAD) appears to be a multifactorial process caused by the interaction of environmental risk factors with multiple predisposing genes. Therefore, in this study we aimed to determine the role of oxidative DNA damage and some variations in glutathione S-transferase (GSTM1 and GSTT1) and DNA repair (hOGG1) genes in CAD risk.