Effects of Acute Malathion Exposure on Renal Oxidant and Antioxidant Balance in Rats

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Pasaoglu O. T., Sen B., Ekremoglu M., Severcan C., Pasaoglu H.

GAZI MEDICAL JOURNAL, cilt.32, sa.2, ss.189-193, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.12996/gmj.2021.42
  • Dergi Adı: GAZI MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.189-193
  • Anahtar Kelimeler: Malathion, organophosphate, pesticide, oxidant-antioxidant balance, kidney, oxidative stress, OXIDATION PROTEIN PRODUCTS, GLYCATION END-PRODUCTS, INDUCED LIPID-PEROXIDATION, BIOCHEMICAL-EVIDENCE, PARAOXONASE ACTIVITY, STRESS, TISSUES, TOXICITY, KIDNEY, LIVER
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Pesticides have been used in agriculture to enhance food production by eradicating undesired insects and controlling disease vectors. Malathion is one of the most widely used organophosphate pesticides. However, it has been postulated that organophosphate pesticides lead to oxidative stress through formation of excessive reactive oxygen species and disrupting the antioxidant defense systems.