Effects of Acute Malathion Exposure on Renal Oxidant and Antioxidant Balance in Rats


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Pasaoglu O. T. , Sen B., Ekremoglu M., Severcan C., Pasaoglu H.

GAZI MEDICAL JOURNAL, vol.32, no.2, pp.189-193, 2021 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.12996/gmj.2021.42
  • Journal Name: GAZI MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.189-193
  • Keywords: Malathion, organophosphate, pesticide, oxidant-antioxidant balance, kidney, oxidative stress, OXIDATION PROTEIN PRODUCTS, GLYCATION END-PRODUCTS, INDUCED LIPID-PEROXIDATION, BIOCHEMICAL-EVIDENCE, PARAOXONASE ACTIVITY, STRESS, TISSUES, TOXICITY, KIDNEY, LIVER
  • Gazi University Affiliated: No

Abstract

Objective: Pesticides have been used in agriculture to enhance food production by eradicating undesired insects and controlling disease vectors. Malathion is one of the most widely used organophosphate pesticides. However, it has been postulated that organophosphate pesticides lead to oxidative stress through formation of excessive reactive oxygen species and disrupting the antioxidant defense systems.