Doppler ultrasound is known as a reliable technique, which demonstrates the flow characteristics and resistance of ophthalmic arteries. In this study, ophthalmic arterial Doppler signals were obtained from 95 subjects - that 45 of them had suffered from Uveitis disease and the rest of them had been healthy subjects. Multilayer perceptron neural network (MLPNN) employing quick propagation training algorithm was used to detect the presence of Uveitis disease. Spectral analysis of ophthalmic arterial Doppler signals was performed by autoregressive moving average (ARMA) method for determining the MLPNN inputs. The MLPNN was trained with training set, cross validated with cross validation set and tested with testing set. All these data sets were obtained from ophthalmic arteries of healthy subjects and subjects suffering from Uveitis disease. Performance indicators and statistical measures were used for evaluating the MLPNN. The correct classification rate was 95.83% for healthy subjects and 91.30% for subjects suffering from Uveitis disease. Based on the accuracy of the MLPNN detections, it can be mentioned that the classification of ophthalmic arterial Doppler signals with Uveitis disease is feasible by the MLPNN employing quick propagation training algorithm.