The Relationship Between Orexin-A Levels, Nutritional Status and Quality of Sleep in Hemodialysis Patients


GÜLBAHAR Ö., Mutluay R., Sayin A., Konca C., DERİCİ Ü., Sindel S., ...More

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.35, no.2, pp.131-137, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 2
  • Publication Date: 2010
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.131-137
  • Gazi University Affiliated: Yes

Abstract

Objective: Symptoms such as anorexia and sleep disturbances are common and cause a significant reduction in quality of life in hemodialysis patients. Orexin-A, which is a neuropeptide produced in lateral hypothalamic neurons and involved in regulation of feeding behavior, energy metabolism and sleep-wake cycle, is a good candidate to play a role in sleep and feeding disturbances in these patients. The aim of this study was to investigate the relationship between orexin-A levels and anorexia and sleep disturbances in hemodialysis patients.