Protective effect of omega-3 fatty acids on diethylnitrosamine toxicity in rats

Atakisi O., Atakisi E., Ozcan A., Karapehlivan M., Kart A.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, cilt.17, sa.4, ss.467-471, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 4
  • Basım Tarihi: 2013
  • Dergi Adı: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.467-471
  • Anahtar Kelimeler: Diethylnitrosamine, Omega-3 fatty acids, Nitric oxide, Rat, POLYUNSATURATED FATTY-ACIDS, NITRIC-OXIDE, FISH-OIL, OXIDANT/ANTIOXIDANT STATUS, N-NITROSODIETHYLAMINE, ENZYME-ACTIVITIES, SUPPLEMENTATION, ANTIOXIDANTS, DONORS, AGENTS
  • Gazi Üniversitesi Adresli: Hayır

Özet

OBJECTIVES: In this study, it was aimed to investigate the effect of n-3 fatty acids (n-3 FA) on diethylnitrosamine (DEN) toxicity with respect to alterations including nitric oxide (NO) formation, uric acid level as well as some liver related enzymes such as aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) activities in rats.