Stobadine protects rat kidney against ischaemia/reperfusion injury


Guz G., Demirogullari B., Ulusu N. N. , Dogu C., Demirtola A., Kavutcu M. , ...Daha Fazla

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, cilt.34, ss.210-216, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 34 Konu: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1440-1681.2007.04574.x
  • Dergi Adı: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Sayfa Sayıları: ss.210-216

Özet

1. Ischaemia-reperfusion (I/R) injury, one of the main causes of acute renal failure, still needs satisfactory treatment for routine clinical application. Stobadine, a novel synthetic pyridoindole anti-oxidant, has the ability to reduce tissue injury induced by mechanisms involving reactive oxygen species during I/R. The aim of the present study was to determine the effects of stobadine on renal I/R injury.