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Taskin B. D., KULA S., ERGÜN M. A., Altun D., Olgunturk R., TUNAOĞLU F. S., ...More
ANATOLIAN JOURNAL OF CARDIOLOGY, vol.16, no.10, pp.791-796, 2016 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
16
Issue:
10
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Publication Date:
2016
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Doi Number:
10.14744/anatoljcardiol.2015.6150
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Journal Name:
ANATOLIAN JOURNAL OF CARDIOLOGY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
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Page Numbers:
pp.791-796
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Keywords:
CYP2C9, genetic polymorphism, INR, pharmacogenetics, VKORC1, warfarin, PATIENT CHARACTERISTICS, TURKISH POPULATION, IMPACT, FREQUENCY, GENOTYPES, VARIANTS
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Gazi University Affiliated:
Yes
Abstract
Objective: The aim was to investigate the frequency of genetic polymorphisms of cytochrome P4502C9 (CYP2C9) and vitamin K epoxide reductase complex subunit1 (VKORC1) and determine the effect of these polymorphisms on warfarin dose requirements in pediatric patients.