The effect of CYP2C9 and VKORC1 genetic polymorphisms on warfarin dose requirements in a pediatric population


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Taskin B. D. , KULA S. , ERGÜN M. A. , Altun D., Olgunturk R., TUNAOĞLU F. S. , ...More

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.16, no.10, pp.791-796, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 10
  • Publication Date: 2016
  • Doi Number: 10.14744/anatoljcardiol.2015.6150
  • Title of Journal : ANATOLIAN JOURNAL OF CARDIOLOGY
  • Page Numbers: pp.791-796

Abstract

Objective: The aim was to investigate the frequency of genetic polymorphisms of cytochrome P4502C9 (CYP2C9) and vitamin K epoxide reductase complex subunit1 (VKORC1) and determine the effect of these polymorphisms on warfarin dose requirements in pediatric patients.