Pentoxifylline attenuates mucosal damage in an experimental model of rat colitis by modulating tissue biomarkers of inflammation, oxidative stress, and fibrosis


Karatay E., Gul Utku O., Erdal H., ARHAN M., Onal I. K., İBİŞ M., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.47, no.1, pp.348-356, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.3906/sag-1508-98
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.348-356
  • Keywords: Fibrosis, inflammatory bowel diseases, matrix metalloproteinases, pentoxifylline, transforming growth factor beta, tumor necrosis factor-alpha, BOWEL-DISEASE, CROHNS-DISEASE, COLON, OXPENTIFYLLINE, METAANALYSIS, ALPHA, IBD
  • Gazi University Affiliated: Yes

Abstract

Background/aim: This study was designed to identify the effect of pentoxifylline on trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats.