Matrix metalloproteinase-9 expression correlated with tumor response in patients with locally advanced rectal cancer undergoing preoperative chemoradiotherapy

Unsal, Diclehan; Uner, Aytug; Akyurek, NALAN; Erpolat, ÖZGE; Dursun, Ayse; Pak, Yucel

doi:10.1016/j.ijrobp.2006.08.010

Matrix metalloproteinase-9 expression correlated with tumor response in patients with locally advanced rectal cancer undergoing preoperative chemoradiotherapy

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Unsal D., Uner A., Akyurek N., Erpolat P., Dursun A., Pak Y.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, vol.67, no.1, pp.196-203, 2007 (SCI-Expanded)

Publication Type: Article / Article
Volume: 67 Issue: 1
Publication Date: 2007
Doi Number: 10.1016/j.ijrobp.2006.08.010
Journal Name: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.196-203
Keywords: rectal cancer, radiotherapy, matrix metalloproteinase, gelatinase, preoperative treatment, HUMAN COLORECTAL-CANCER, MATRIX METALLOPROTEINASES, TISSUE INHIBITOR, CHEMORADIATION, CARCINOMA, GELATINASES, REGRESSION, MATRILYSIN, SURVIVAL, THERAPY
Gazi University Affiliated: Yes

Abstract

Purpose: To analyze whether the expression of matrix metalloproteinases (MMPs) and their tissue inhibitors are associated with tumor response to preoperative chemoradiotherapy in rectal cancer patients.