Characterization of Electrospun Nanofibrous Scaffolds for Nanobiomedical Applications

Sağlam N., Sağlam S., Ateş H., Sağlam N., Saglam N.

JOURNAL OF ELECTRONIC MATERIALS, vol.45, no.8, pp.3835-3841, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 8
  • Publication Date: 2016
  • Doi Number: 10.1007/s11664-016-4549-7
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3835-3841
  • Keywords: Nanotechnology, nanomedicine, electrospinning, nanofiber, characterization, bone reconstruction, CELLS, NANOCOMPOSITE, NANO
  • Gazi University Affiliated: Yes


The electrospinning method is employed in the production of porous fiber scaffolds, and the usage of electrospun scaffolds especially as drug carrier and bone reconstructive material such as implants is promising for future applications in tissue engineering. The number of publications has grown very rapidly in this field through the fabrication of complex scaffolds, novel approaches in nanotechnology, and improvements of imaging methods. Hence, characterization of these materials has also grown significantly important for getting satisfied and accurate results. This advantageous and versatile method is ideal for mimicking bone extracellular matrix, and many biodegradable and biocompatible polymers are preferred in the field of bone reconstruction. In this study, gelatin, gelatin/nanohydroxyapatite (nHAp) and gelatin/PLLA/nHAp scaffolds were fabricated by the electrospinning process. These composite fibers showed clear and continuous morphology according to observation through a scanning electron microscope and their component analyses were also determined by Fourier transform infrared spectrometer analyses. These characterization experiments revealed the great effects of the electrospinning method for biomedical applications and have an especially important role in bone reconstruction and production of implant coating material.