Randomized, placebo-controlled treatment of anal fissure by lidocaine, EMLA, and GTN in children

Sonmez K., Demirogullari B., EKİNGEN YILDIZ G., Turkyilmaz Z., Karabulut R., Basaklar A., ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.37, sa.9, ss.1313-1316, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 9
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1053/jpsu.2002.34997
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1313-1316
  • Anahtar Kelimeler: anal fissure, EMLA, nitric oxide, glyceryl trinitrate, GLYCERYL-TRINITRATE OINTMENT, CONTROLLED TRIAL, SPHINCTEROTOMY, PATHOGENESIS
  • Gazi Üniversitesi Adresli: Evet

Özet

Background/Purpose: Anal fissures would result in constipation in children, worsening the clinical picture, thus, justifying a fast response therapy. In this randomized, prospective, placebo-controlled study, it was aimed to determine the response rates to fissure treatment by liclocaine, EMLA and GTN on the 10th day and after 8 weeks of therapy. Related childhood literature is scarce, and EMLA is tried for the first time in fissure treatment.