Randomized, placebo-controlled treatment of anal fissure by lidocaine, EMLA, and GTN in children

Sonmez K., Demirogullari B., EKİNGEN YILDIZ G., Turkyilmaz Z., Karabulut R., Basaklar A., ...More

JOURNAL OF PEDIATRIC SURGERY, vol.37, no.9, pp.1313-1316, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 9
  • Publication Date: 2002
  • Doi Number: 10.1053/jpsu.2002.34997
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1313-1316
  • Keywords: anal fissure, EMLA, nitric oxide, glyceryl trinitrate, GLYCERYL-TRINITRATE OINTMENT, CONTROLLED TRIAL, SPHINCTEROTOMY, PATHOGENESIS
  • Gazi University Affiliated: Yes


Background/Purpose: Anal fissures would result in constipation in children, worsening the clinical picture, thus, justifying a fast response therapy. In this randomized, prospective, placebo-controlled study, it was aimed to determine the response rates to fissure treatment by liclocaine, EMLA and GTN on the 10th day and after 8 weeks of therapy. Related childhood literature is scarce, and EMLA is tried for the first time in fissure treatment.