Groundwater is an important component of the global freshwater supply and is affected by climate. There is a strong need to understand and evaluate the impacts of climate change over the long term, in order to better plan and manage precious groundwater resources. Turkey, located in Mediterranean basin, is threatened by climate change. The purpose of this study was, through a quantitative overview, to determine the impacts of climate change on the groundwater recharge rates in Kucuk Menderes River Basin in western Turkey. According to the data of odemi and Selcuk meteorological stations located in the basin, there is a significantly decreasing trend in precipitation combined with increasing trends in temperature and evaporation observed in 1964-2011. The calculations of groundwater recharge with hydrologic budget method for the observation period showed an approximately 15% decline in groundwater recharge in the basin. Thus, the combined impacts of climate change and excessive groundwater pumping, due to increasing water demand, have caused a significant decline in groundwater levels. Consequently, the proper management of the groundwater resources threatened by climate change requires effective governance to both mitigate the adverse impacts of climate change and facilitate the adaptation of sustainable integrated water management policies.