SISTER-CHROMATID EXCHANGES IN EPILEPTIC PATIENTS ON ANTICONVULSANT THERAPY

SARDAS, S; ADA, M; KARAKAYA, AE; AYDIN, N

doi:10.1016/0165-1161(94)90029-9

SISTER-CHROMATID EXCHANGES IN EPILEPTIC PATIENTS ON ANTICONVULSANT THERAPY

Atıf İçin Kopyala

SARDAS S., ADA M., KARAKAYA A., AYDIN N.

MUTATION RESEARCH-ENVIRONMENTAL MUTAGENESIS AND RELATED SUBJECTS, cilt.313, sa.1, ss.21-24, 1994 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 313 Sayı: 1
Basım Tarihi: 1994
Doi Numarası: 10.1016/0165-1161(94)90029-9
Dergi Adı: MUTATION RESEARCH-ENVIRONMENTAL MUTAGENESIS AND RELATED SUBJECTS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
Sayfa Sayıları: ss.21-24
Gazi Üniversitesi Adresli: Hayır

Özet

Sister-chromatid exchanges (SCE) have been studied to analyze genotoxic effects in epileptic patients on anticonvulsant therapy. All patients had an increased frequency of SCE per metaphase (p < 0.001) compared to controls, indicating a genotoxic effect of anticonvulsant drugs.