ANTIOXIDANT DEFENCE SYSTEMS, LIPID PEROXIDATION AND ACETYLCHOLINESTERASE ACTIVITY OF OREOCHROMIS NILOTICUS EXPOSED TO MERCURY AND MERCURY plus SELENIUM


FİRİDİN G., KARGIN F., FIRAT Ö., ÇOĞUN H. Y., FIRAT Ö., FİRİDİN B., ...Daha Fazla

FRESENIUS ENVIRONMENTAL BULLETIN, cilt.24, ss.1958-1965, 2015 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24
  • Basım Tarihi: 2015
  • Dergi Adı: FRESENIUS ENVIRONMENTAL BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.1958-1965
  • Gazi Üniversitesi Adresli: Evet

Özet

The objective of the present study was to evaluate the oxidative stress potential of mercury (Hg) exposure with the modulatory effect of selenium (Se) in the brain and kidney tissues of Oreochromis niloticus. The fish were exposed to 0.01 and 0.1 mg/L Hg, 0.01 mg/L Hg+0.1 mg/L Se, and 0.1 mg/L Hg+1.0 mg/L Se, for 7 and 14 days. The activities of total glutathione (tGSH), malondialdehyde (MDA) and catalase (CAT), glutathione S-transferase (GST), and acetylcholinesterase (AChE) were measured from samples of the tissues. The results indicated that all concentrations of Hg caused a time-dependent increase in CAT, GST activity, whereas AChE. activity and tGSH content were decreased in brain and kidney tissues. MDA levels in tissues of fish exposed to Hg+Se mixtures were lower compared to those exposed to Hg only. Selenium application in combination with mercury provided an alleviation of the toxic effects of mercury in the investigated tissues for biochemical parameters.