Composition and antimicrobial activity of the oils of Ferula szowitsiana DC. from Turkey

Oezek G., Oezek T., Iscan G., Baser K. H. C. , Duran A., Hammoglu E.

JOURNAL OF ESSENTIAL OIL RESEARCH, cilt.20, sa.2, ss.186-190, 2008 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Konu: 2
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1080/10412905.2008.9699987
  • Sayfa Sayıları: ss.186-190


The essential oils from the leaves and steins of Ferula szowitsiana DC. (Umbelliferae) were separately obtained by hydrodistillation and then analyzed by GC and GC/MS methods. The oil yields were 0.4% and 0.05%, respectively. One-hundred and sixty-two compounds representing 99.5% and 99 compounds representing 94.4% were identified in the leaf oil and stem oil, respectively, with beta-eudesmol (32.0% and 29.5%, resp.), alpha-eudesmol (18.2% and 16.6%, resp.) and alpha-pinene (8.6% and 6.4%, resp.) as the major constituents. Antimicrobial activity of the leaf oil was tested via in-vitro microdilution broth technique. Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris, Salmonella typhimurium, Staphylococcus epidermidis, Methicillin-resistant Staphylococcus aureus, and Candida albicans were used as the test microorganisms.