Effect of combined exercise training on serum brain-derived neurotrophic factor, suppressors of cytokine signaling 1 and 3 in patients with multiple sclerosis

Ozkul Ç., Guclu-Gunduz A., Irkec C., Fidan I., Aydin Y., Ozkan T., ...More

JOURNAL OF NEUROIMMUNOLOGY, vol.316, pp.121-129, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 316
  • Publication Date: 2018
  • Doi Number: 10.1016/j.jneuroim.2018.01.002
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.121-129
  • Keywords: Multiple sclerosis, Suppressors of cytokine signaling, Brain-derived neurotrophic factor, Exercise, Physical performance, Fatigue, QUALITY-OF-LIFE, RANDOMIZED CONTROLLED-TRIAL, FATIGUE SEVERITY SCALE, THERAPEUTIC IMPLICATIONS, 6-MINUTE WALK, EXPRESSION, GUIDELINES, BLOOD, SOCS, ASSOCIATION
  • Gazi University Affiliated: Yes


Background: Suppressors of cytokine signaling (SOCS) and brain-derived neurotrophic factor (BDNF) are important immunologic, and neurotrophic factors for MS pathogenesis. The impact of exercise on these factors is yet to be fully elucidated in patients with MS.