When Occupational Health and Safety studies are examined, it is seen that many different methods are employed in the risk analysis process, but there is no study in the literature to estimate the amount of Personal Protective Equipment (PPE) usage, which is one of the precautions to be taken after risk analysis. In this study, a model was developed based on Autoregressive Integrated Moving Averages (ARIMA) for estimation of PPE usage of enterprises. In an enterprise operating in the white goods sector, the usage data of respiratory protective masks in 2015-2019 has been examined and the need for respiratory protective masks that may arise for 2020-2022 has been estimated. The effectiveness of our method was examined by comparing the estimates made with the amount of PPE usage. Increasing relationships between man and machine in the industrial era require the creation of human-compatible businesses, and in this sense, ergonomics can benefit from occupational health and safety practices in order to improve productivity. The PPE estimates made gave close results to the actual use of respiratory protective masks. This study for the estimation of the amount of use of protective masks can also be applied for the prediction of other personal protective equipment used throughout the business in the future.