Serum vitamin E levels in healthy people (n=71) and patients with cardiovascular diseases (n=62) were determined. The cases of cardiovascular disease comprised patients with acute myocardial infarction (AMI) (n=31), atherosclerosis (AT) (n=23) and myocardial ischaemia (MI) (n=8). The mean (+/-SD) serum vitamin E levels of the control group and the group with cardiovascular disease were 1.12+/-0.27 mg% and 0.98+/-0.41 mg%, respectively. Patients with AMI, AT and MI had corresponding levels of 0.97+/-0.48 mg%, 1.00+/-0.39 mg% and 1.01+/-0.44 mg%, respectively. Overall serum vitamin E levels were lower in the group with cardiovascular disease than in the control group.