The effect of levosimendan on lung damage after myocardial ischemia reperfusion in rats in which experimental diabetes was induced

ALKAN M., ÇELİK A., Bilge M., KİRAZ H. A., KİP G., ÖZER A., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.193, sa.2, ss.920-925, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 193 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.jss.2014.08.038
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.920-925
  • Anahtar Kelimeler: Diabetes mellitus, Levosimendan, Ischemia-reperfusion, Distant organ damage, Rat, Antioxidant system, LIPID-PEROXIDATION, INJURY, ISCHEMIA/REPERFUSION, MICROCIRCULATION, ILOPROST
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: It is known that diabetic complications and lipid peroxidation are closely associated. During ischemia and reperfusion (IR), injury may occur in distant organs, as well as in tissues next to the region exposed to the ischemia, and the lungs can be one of the most affected of these organs. Therefore, this study investigated the effects of levosimendan on lung tissue and the oxidant-antioxidant system in diabetic rats.