Usefulness of the monocyte-to-high-density lipoprotein cholesterol ratio to predict bare metal stent restenosis


Yilmaz S., Akboga M. K. , Sen F., Balci K. G. , Aras D., Temizhan A., ...More

BIOMARKERS IN MEDICINE, vol.10, no.9, pp.959-966, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 9
  • Publication Date: 2016
  • Doi Number: 10.2217/bmm-2016-0069
  • Journal Name: BIOMARKERS IN MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.959-966
  • Keywords: high-density lipoprotein cholesterol, inflammation, monocyte count, stent restenosis, PERCUTANEOUS CORONARY INTERVENTION, ASSOCIATION TASK-FORCE, LYMPHOCYTE RATIO, INFLAMMATORY BIOMARKERS, ANGIOGRAPHIC RESTENOSIS, PRACTICE GUIDELINES, ANGIOPLASTY
  • Gazi University Affiliated: Yes

Abstract

Aim: The aim of the present study was to investigate the predictive value of preprocedural monocyte count-to-high-density lipoprotein cholesterol ratio (MHR) on development of in-stent restenosis in patients undergoing coronary bare-metal stent (BMS) implantation. Patients & methods: Data from 705 patients who had undergone BMS implantation and additional control coronary angiography were analyzed. Results: Patients were divided into three tertiles based on preprocedural MHR. Restenosis occurred in 59 patients (25%) in the lowest tertile, 84 (35%) in the middle tertile and 117 (50%) in the highest MHR tertile (p < 0.001). Using multiple logistic regression analysis, smoking, diabetes mellitus, stent length, preprocedural MHR and C-reactive protein levels emerged as independent predictors of in-stent restenosis. Conclusion: High preprocedural MHR is related to BMS restenosis.