Usefulness of the monocyte-to-high-density lipoprotein cholesterol ratio to predict bare metal stent restenosis


Yilmaz S., Akboga M. K., Sen F., Balci K. G., Aras D., Temizhan A., ...More

BIOMARKERS IN MEDICINE, vol.10, no.9, pp.959-966, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 9
  • Publication Date: 2016
  • Doi Number: 10.2217/bmm-2016-0069
  • Journal Name: BIOMARKERS IN MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.959-966
  • Keywords: high-density lipoprotein cholesterol, inflammation, monocyte count, stent restenosis, PERCUTANEOUS CORONARY INTERVENTION, ASSOCIATION TASK-FORCE, LYMPHOCYTE RATIO, INFLAMMATORY BIOMARKERS, ANGIOGRAPHIC RESTENOSIS, PRACTICE GUIDELINES, ANGIOPLASTY
  • Gazi University Affiliated: No

Abstract

Aim: The aim of the present study was to investigate the predictive value of preprocedural monocyte count-to-high-density lipoprotein cholesterol ratio (MHR) on development of in-stent restenosis in patients undergoing coronary bare-metal stent (BMS) implantation. Patients & methods: Data from 705 patients who had undergone BMS implantation and additional control coronary angiography were analyzed. Results: Patients were divided into three tertiles based on preprocedural MHR. Restenosis occurred in 59 patients (25%) in the lowest tertile, 84 (35%) in the middle tertile and 117 (50%) in the highest MHR tertile (p < 0.001). Using multiple logistic regression analysis, smoking, diabetes mellitus, stent length, preprocedural MHR and C-reactive protein levels emerged as independent predictors of in-stent restenosis. Conclusion: High preprocedural MHR is related to BMS restenosis.