Akademik Veri Yönetim Sistemi
Türk Romatoloji Kongresi 8-12 Mart 2023, , Antalya, Türkiye, 8 - 12 Mart 2023, ss.173-174
Objectives: To investigate possible changes in muscle thickness and pennation angles of
quadriceps femoris (QF) muscle parts in patients with rheumatoid arthritis (RA) after 4 weeks of
resistance training.
Patients and Methods: This study included 12 patients with RA, 12 patients with knee OA as
positive control group and 13 volunteers as healthy control group. All participants were given 4
weeks of quadriceps-hamstring isometric home-based training. At baseline and at the end of the
program, WOMAC and Lequesne algofunctional index scores of knee OA patients and DAS28-CRP
scores of RA patients were recorded. Dominant knee thickness and pennation angle measurements
of QF muscle parts were evaluated by ultrasonography with a linear probe at 6-18 MHz.
Results: After training, the thickness and pennation angle changes of QF parts didn't differ
significantly between groups. Baseline WOMAC and Lequesne scores were 32.7±8.35SD and
11.1±3.06SD respectively. At 4 weeks both scores improved: WOMAC 21.2±8.32SD and Lequesne
7.9±2.1SD. DAS28-CRP scores of RA patients didn’t show any significant changes between baseline
and at 4 weeks. Baseline rectus femoris (RF) and vastus medialis (VM) thickness measurements
were significantly higher in the healthy control group.
Conclusion: Dominant knee RF and VM atrophy were observed in RA and knee OA patients.
Although after 4 weeks of quadriceps-hamstring isometric training, WOMAC and Lequesne index
scores of knee OA patients improved and DAS28-CRP scores of RA patients didn’t show any
significant changes; there was no beneficial effect in muscle architecture.