Clinical and prognostic importance of XIAP and USP8 in advanced stages of non-small cell lung cancer.

Baykara M., Yaman M., Buyukberber S., Tufan G., Demirci U., Benekli M., ...More

Journal of B.U.ON. : official journal of the Balkan Union of Oncology, vol.18, no.4, pp.921-7, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 4
  • Publication Date: 2013
  • Journal Name: Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.921-7
  • Keywords: apoptosis, non-small cell lung cancer, protein degradation, USP8, XIAP, X-LINKED INHIBITOR, APOPTOSIS PROTEINS, SURVIVIN EXPRESSION, DOWN-REGULATION, GENE, BINDING, MARKER, FAMILY, OVEREXPRESSION, SENSITIZATION
  • Gazi University Affiliated: Yes

Abstract

Purpose: To investigate the relationship of the apoptosis regulators X-linked inhibitor of apoptosis (XIAP) and ubiquitin specific protease 8 (USP8) with clinical parameters, survival and response to chemotherapy in patients with advanced stages of non-small cell lung cancer (NSCLC).