Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury


Bolay H. B. , Gursoy-Ozdemir Y., Sara Y., Onur R., Can A., Dalkara T.

STROKE, cilt.33, sa.5, ss.1369-1375, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Konu: 5
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1161/01.str.0000013708.54623.de
  • Dergi Adı: STROKE
  • Sayfa Sayıları: ss.1369-1375

Özet

Background and Purpose-Synaptic transmission is highly vulnerable to metabolic perturbations. However, the long-term consequences of transient metabolic perturbations on synapses are not clear. We studied the long-lasting changes in synaptic transmission and phosphorylation of presynaptic proteins in penumbral cortical neurons after transient moderate ischemia.