Association between the 196G > A (VAL66 MET) and -1360C > T (C-270T) polymorphisms of the brain-derived neurotrophic factor gene and bipolar disorder

Demiryurek, Seniz; Savas, Haluk; Igci, Mehri; Herken, Hasan; Gorucu, Senay; Kara, Ali; Selek, Salih; Oguzkan, Sibel; Bulbul, Feridun; Arslan, Ahmet; Demiryurek, Abdullah

Association between the 196G > A (VAL66 MET) and -1360C > T (C-270T) polymorphisms of the brain-derived neurotrophic factor gene and bipolar disorder

Atıf İçin Kopyala

Demiryurek S., Savas H. A., Igci M., Herken H., Gorucu S., Kara A. F., ...Daha Fazla

NEUROLOGY PSYCHIATRY AND BRAIN RESEARCH, cilt.13, sa.3, ss.125-130, 2006 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 13 Sayı: 3
Basım Tarihi: 2006
Dergi Adı: NEUROLOGY PSYCHIATRY AND BRAIN RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.125-130
Gazi Üniversitesi Adresli: Hayır

Özet

Backgrounds: Bipolar disorder is a severe psychiatric disease, characterized by recurrent manic and depressive episodes, and is believed to have a strong genetic component. Several data suggest that the brain-derived neurotrophic factor (BDNF) gene is a potential candidate gene for this affective disease. The aim of this study was to test a possible association between the BDNF gene polymorphisms and bipolar disorder in a Turkish population.