Synthesis, characterization and antimicrobial activity of a Zn(II) complex with 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone
JOURNAL OF COORDINATION CHEMISTRY, cilt.61, sa.20, ss.3276-3283, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 61 Sayı: 20
- Basım Tarihi: 2008
- Doi Numarası: 10.1080/00958970802032678
- Dergi Adı: JOURNAL OF COORDINATION CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.3276-3283
- Gazi Üniversitesi Adresli: Evet
Özet
A new Zn(II) complex with 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone [Zn(NO3)(H2O)(C10H11N5S)]NO3 was prepared and characterized by elemental analyses, FT-IR, H-1 NMR spectroscopy, thermogravimetric analysis (TGA), X-ray diffraction (XRD), and single-crystal X-ray diffraction analysis. The coordination geometry of the pentacoordinated zinc is a distorted square pyramid. The antimicrobial activity of the complex was evaluated using a broth micro-dilution method against a panel of human pathogenic Gram positive, Gram negative bacteria and the yeast Candida albicans. The best inhibitory effect was observed against Enterobacter aerogenes (MIC = 0.031 mg mL(-1)).