Visceral Leishmaniasis Mimicking Autoimmune Hepatitis, Primary Biliary Cirrhosis, and Systemic Lupus Erythematosus Overlap

GÜZEL TUNÇCAN Ö., TUFAN A., Telli G., AKYÜREK N., Pamukcuolu M., Yilmaz G., ...More

KOREAN JOURNAL OF PARASITOLOGY, vol.50, no.2, pp.133-136, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.3347/kjp.2012.50.2.133
  • Journal Name: KOREAN JOURNAL OF PARASITOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.133-136
  • Keywords: Leishmania, visceral leishmaniasis, systemic lupus erythematosus, autoimmune hepatitis, primary biliary cirrhosis, LIPOSOMAL AMPHOTERICIN-B
  • Gazi University Affiliated: Yes

Abstract

Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena. To date, VL mimicking or exacerbating various autoimmune diseases have been described, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and autoimmune hepatitis (AIH). Herein, we presented a patient with VL who had overlapping clinical features with SLE, AIH, as well as antimitochondrial antibody (AMA-M2) positive primary biliary cirrhosis.