Outcomes and Safety of Living Donor Hepatectomy for Liver Transplantation: A Single-Center Experience


Creative Commons License

Kozan R., Sozen H., Sar S., Gurkan O. E., Akkan K., Ozturk H., ...Daha Fazla

IRANIAN RED CRESCENT MEDICAL JOURNAL, cilt.64, ss.1-5, 2024 (SCI-Expanded)

Özet

Background and Objectives: Donor hepatectomy for living related liver transplantation (LRLT) has been using widely worldwide, particularly in countries that face a shortage of deceased donors. In this study, the outcomes and safety of donor hepatectomy were aimed to be examined.  Methods: Total of 69 donor hepatectomies have been performed between 2006 and 2020. All data were collected retrospectively from hospital charts. Donor evaluation starts with whole blood tests, viral load, blood group analysis. Later, all donors evaluated by the transplantation surgery, gastroenterology, pulmonary, cardiologic and psychiatric teams. Results: Of the 69 living liver donors, 28 (41%) were female, 41 (59%) were male, 39 (57%) for pediatric and 30 (43%) for adult recipient, respectively. The mean age of the donor was 35 ± 10.5 years (range, 2160). Among the donors, 25 (36%) donors underwent to right lobectomy without middle hepatic vein, 28 (41%) left lobectomy and in 16 (23%) left lateral (LL) lobectomy. Totally 8 (12%) surgical complications were seen (n=6 early, n=2 late complication) in median 100 months (range 44-205) follow-up period.  Conclusion: Our study demonstrates favorable outcomes and safety profiles of donor hepatectomy for LRLT at our center. The meticulous evaluation process, comprehensive surgical planning, and multidisciplinary approach contribute to the success of the procedure.