Interaction of lidocaine with reactive oxygen and nitrogen species

Günaydın D. B., Demiryurek A.

EUROPEAN JOURNAL OF ANAESTHESIOLOGY, cilt.18, ss.816-822, 2001 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1046/j.1365-2346.2001.00931.x
  • Dergi Adı: EUROPEAN JOURNAL OF ANAESTHESIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.816-822
  • Anahtar Kelimeler: anaesthetics, local, lidocaine, blood cells, leukocytes, free radicals, luminescence, chemiluminescence, SUPEROXIDE ANION PRODUCTION, HUMAN POLYMORPHONUCLEAR LEUKOCYTES, LOCAL-ANESTHETICS, CHEMI-LUMINESCENCE, HUMAN NEUTROPHILS, LYSOSOMAL-ENZYME, NITRIC-OXIDE, CHEMILUMINESCENCE, PEROXYNITRITE, INHIBITION
  • Gazi Üniversitesi Adresli: Evet

Özet

Background and objective To investigate the ability of lidocaine to inhibit reactive oxygen and/or nitrogen species generation by either human leukocytes or cell-free systems via luminol- and lucigenin-enhanced chemiluminescence.