Mitomycin C decreases the rate of stricture formation in caustic esophageal burns in rats

TÜRKYILMAZ Z., SÖNMEZ K., KARABULUT R., Guelbahar Ö., POYRAZ A., Sancak B., ...Daha Fazla

SURGERY, cilt.145, sa.2, ss.219-225, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 145 Sayı: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.surg.2008.10.007
  • Dergi Adı: SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.219-225
  • Gazi Üniversitesi Adresli: Evet

Özet

Background. Although the incidence of caustic ingestion is declining, the management of caustic esophageal strictures remains a challenge. Although many agents have been tried experimentally to treat strictures, few have gained clinical application. The aim of this study was to investigate the influence of mitomycin C (MMC), which inhibits fibroblastic proliferation in treating delayed caustic esophageal strictures.