Mitomycin C decreases the rate of stricture formation in caustic esophageal burns in rats
SURGERY, cilt.145, sa.2, ss.219-225, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 145 Sayı: 2
- Basım Tarihi: 2009
- Doi Numarası: 10.1016/j.surg.2008.10.007
- Dergi Adı: SURGERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.219-225
- Gazi Üniversitesi Adresli: Evet
Özet
Background. Although the incidence of caustic ingestion is declining, the management of caustic esophageal strictures remains a challenge. Although many agents have been tried experimentally to treat strictures, few have gained clinical application. The aim of this study was to investigate the influence of mitomycin C (MMC), which inhibits fibroblastic proliferation in treating delayed caustic esophageal strictures.