Effect of vitamin D on free radical metabolism in renal tissues of septic rats


Atikeler G., Ciraci M. Z. , Kocabiyik M., KAVUTÇU M. , CANBOLAT O. , Cevik C.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.41, ss.316-321, 2016 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 41 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1515/tjb-2016-0046
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Sayfa Sayıları: ss.316-321

Özet

Objective: Sepsis is a common cause of morbidity and mortality in the intensive care unit. Lipopolysaccharide (LPS)-induced excessive immune response is associated with multi-organ damage in sepsis. Excessive immune response causes multi-organ damage by increasing oxidative stress. Studies on the antioxidant effects of vitamin D demonstrated its protective role. In this study we aimed to investigate the effects of vitamin D on free radical metabolism in LPS injected rats.