Effects of rosiglitazone pretreatment on blood glucose, lipid levels, urea, and microalbuminuria in rats undergoing 70% pancreatectomy

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Acar H. Z., ŞENEL O. O., BUKAN N., Yurekli B., Salman A. E., Yetisir F.

OPEN ACCESS SURGERY, cilt.6, ss.1-5, 2013 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6
  • Basım Tarihi: 2013
  • Doi Numarası: 10.2147/oas.s39364
  • Dergi Adı: OPEN ACCESS SURGERY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.1-5
  • Anahtar Kelimeler: rosiglitazone, partial pancreatectomy, diabetes
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Partial pancreatectomy is one of the main causes of type II diabetes, which occurs because of insulin deficiency due to a decrease in the number of beta-cells. Partial pancreatectomy is the treatment of choice particularly for pancreatic cysts, benign and malign tumors of the pancreas, and pancreatic abscesses. Morbidity and mortality associated with pancreatectomy increases as a result of diabetes and its complications.